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Home / Health / The surface of the “double mutation” coronavirus variant in the Bay Area.This is what we know

The surface of the “double mutation” coronavirus variant in the Bay Area.This is what we know



There is another variant related to the coronavirus in the Bay Area.

Stanford University health care spokesperson Lisa Kim said on Sunday that through genome sequencing, the Stanford University Clinical Virology Laboratory has identified and confirmed an emerging mutation that originated in India. Stanford University is screening seven other speculative cases. The location of the confirmed case was not disclosed.

This variant is called a “double mutant” because it carries two mutations in the virus that help it lock itself onto the cell. It may be the cause of the disturbing new increase in Indian cases. Jin said it is unclear whether the variant is more infectious or resistant to vaccine antibodies.

UCSF infectious disease expert Peter Chin-Hong said the variant appears to be more contagious because it accounts for 20% of cases in the hard-hit states of Maharashtra. Qin Hong said that the number of cases there has increased by more than 50% in the past week.

He wrote in an email: “From a biological point of view, because these two mutations act on the receptor binding domain of the virus, they have greater spreadability, but so far, there is no official Communication research.”

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Chin-Hong said that it is too early to determine whether the variant is more resistant to vaccine antibodies or will cause reinfection, but a mutation in this variant is similar to one of the variants first discovered in Brazil and South Africa. , Another mutation is that this variant was also found in a variant first discovered in California.

He said: “This Indian variant contains two mutations in the same virus for the first time, previously seen in separate variants.” “Because we know that the affected domain is the part that the virus uses to enter the human body, and the California variant The body already has higher resistance to certain vaccine antibodies, so it seems reasonable to think that the Indian variant might be that too.”

He said that so far, no studies have confirmed this. Chin-Hong still said that this variant seems likely to be more regional, because the B.1.1.7 variant that originated in the UK has more advantages in India. Although it is not yet certain whether the variant is resistant to the vaccine, he is “optimistic” that the vaccine will work, because people already know that the vaccine’s efficacy against variants originating from South Africa and California is well known.

The latest discoveries have added worrying variants that have entered the United States, including the widespread B.1.1.7. Variation, infectivity increased by 50%. Both the P.1 virus originating in Brazil and the P.1 virus from South Africa have been found in the Gulf region, and both are considered to be resistant to vaccines.

There are many variants from California across the state that are more infectious and may be resistant to vaccines; the variants from New York found in Santa Clara County may also be vaccine resistant.

Kellie Hwang is a writer for the San Francisco Chronicle. Email: kellie.hwang@sfchronicle.com Twitter: @KellieHwang




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