Now, scientists have awakened Fleming’s primitive Penicillium and sequenced its genome for the first time. They say that the information they collect may help fight antibiotic resistance.
Professor Tim Barraclough (Tim Barraclough) said: “After all this time in the refrigerator, it will quickly resume growth. It is easy, just take it out of the test tube and put it in a petri dish. Just go.” The Department of Life Sciences, Imperial University, London and the Department of Zoology, Oxford University.
“To our surprise, despite its historical importance to the primitive Penicillium, no one has sequenced its genome.”
Fleming discovered penicillin in 1928 while working at St. Mary̵
Fight against super bacteria
The research team used genetic information to compare Fleming’s mold with two Penicillium strains from the United States, which are used to produce antibiotics on an industrial scale.
Balaklava said they are looking for differences that naturally evolve over time, which will shed light on how to modify the production of antibiotics to help fight superbugs.
He said: “This may provide us with some suggestions on how to try to improve our use or design anti-bacterial antibiotics.”
“People are always trying to find new and new antibiotics. But when each antibiotic is put into use, after a period of time (five to ten years), the same thing will happen. ,” he added.
His team “is studying the possible subtle differences in a class of antibiotics, and how they change in nature, and whether we can use these subtle differences to slightly change the balance of these bacteria.”
He said: “Maybe it’s time for anyone in the store to buy penicillin.” It is resistant.”