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Research shows that people who have been infected with COVID-19 may only need to be vaccinated once



Six recent studies have shown that people already infected with COVID-19 may not need a second dose of the vaccine.

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The federal government has not changed the recommended dose of the second dose, but studies studying the immune response have shown that although the first dose can greatly improve people who have recovered from COVID-19, the second dose is no different.

Dr. Paul Offett, director of the Vaccine Education Center at the Children’s Hospital of Philadelphia, said: “I think this is completely reasonable.”

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He said that for people who have been vaccinated with COVID-19, the first shot is like a booster vaccine for people who use COVID-19 for the first time – they may even have the side effects of a second dose of the vaccine.

Offit said: “You can reasonably argue that people who can prove that they have been infected (that is, people with antiviral antibodies) can reasonably get a dose.”

Florian Cramer, who led a new study, said that for people with COVID-19, there is no danger in getting another injection. But this may not give you a reservation, and the time and pressure of traveling to and from the vaccination location and watching the needle puncture will bring any benefit.

Everyone who doesn’t need a second shot means someone else’s first shot.

He and others said the challenge will be to determine who does not need a second dose.

“Implementation may not be that easy,” said Cramer, a professor of microbiology at Icahn School of Medicine at Mount Sinai in New York City.

Anyone who has received a formal diagnosis of COVID-19-not just those who felt bad a few days ago and thought they were infected with COVID-19-or those who have antibodies to the virus that causes COVID-19 may skip the first Two shots.

Krammer said that last spring, antibody tests were not always reliable, but the tests that are still on the market are good, although it is not clear whether a specific level of antibody needs to be protected.

Antibody tests (also called serological tests) detect the proteins made by the immune system in response to infections.

According to Krammer’s research, the research was released at the beginning of the month, but it has not yet been peer reviewed. According to the study, people who have previously been infected with the first shot have a similar immune response to those who have not received the second shot of COVID-19. They even have the side effects of the second shot in the first shot.

The study found that the second shot hardly added additional protection.

It concluded: “Changing the policy of giving these people only one dose of vaccine will not have a negative impact on their antibody titers, will not save them from unnecessary suffering, and will release many much-needed vaccine doses.”

Dr. Francis Collins, Dean of the National Institutes of Health, wrote about the research in his weekly blog.

“Although more research needs to be done-I definitely do not recommend changing the current recommendation-the result increases the possibility that for people who have been infected with SARS-CoV-2 and have developed antibodies against SARS-CoV-2 One dose may be enough for the virus,” Collins wrote.

He added: “However, any serious consideration of this option will require more data. This will also be decided by expert advisors from the FDA and the Centers for Disease Control and Prevention (CDC).”

It is not clear how much data or what type of information is sufficient to convince regulators.

more: If you still need to wear a mask, why should you get the COVID-19 vaccine?Health experts say it’s better than being sick

Another new study is a preprint from the University of Maryland, showing that 41 medical staff who recovered from COVID-19 had more antibodies after the first injection than 69 of their counterparts who were not infected with the virus during the second time. .

A preprint from the Fred Hutchinson Cancer Research Center in Seattle found that the blood of people who have recovered from the COVID-19 virus is not as good as the blood of people who have recovered and vaccinated from South Africa to neutralize the original virus or a variant derived from South Africa. . Three other studies have similar findings.

Cramer said: “Each of the six studies published this month look at this issue in a different way, but, “They all basically show the same thing. “

Contact Karen Weintraub at kweintraub@usatoday.com.

Funding from the Masimo Ethics, Innovation and Healthcare Foundation has made USA Today’s health and patient safety partly realized. The Masimo Foundation does not provide editorial opinions.



A person wearing a teddy bear wearing a blue hat: On February 24, Los Angeles health workers were vaccinated against COVID-19.


©Damian Dovarganes/Associated Press
Health workers in Los Angeles were vaccinated against COVID-19 on February 24.

This article was originally published in USA Today: Research shows that people who have been infected with COVID-19 may only need to be vaccinated once

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