Regeneron Pharmaceuticals said on Friday that it has suspended clinical studies of its antibody drug, which is used to treat some of the sickest COVID-19 patients, due to potential safety concerns.
The independent monitoring committee’s recommendation marks the second suspension of clinical trials of experimental coronavirus antibody drugs due to safety issues.
Regeneron said that after the independent monitoring committee observed “there are currently potential safety signals and unfavorable risk/benefit conditions”, the registration of hospitalized COVID-1
The monitoring committee recommends collecting other data about the patients who have been enrolled.
The suspension will not affect other research on regenerative antibody drugs, which is considering emergency use authorization for mild to moderate outpatients with a high risk of adverse results.
The company said earlier this week that another study clearly showed a significant reduction in viral load and the need for further medical attention.
The Data Monitoring Committee also recommends continuing trial registration for hospitalized patients who require little or no oxygen.
Earlier this month, another supervisory committee recommended that a study on Eli Lilly’s antibody drugs be suspended to investigate possible safety issues in hospitalized patients.
on MondayThe study, funded by the National Institute of Allergy and Infectious Diseases (NIAID), announced that there are no longer safety issues, but because the committee has little clinical benefit in treatment, the study has been terminated.
Monoclonal antibodies are one of the main defenses of the laboratory against pathogens.
No antibody drugs have been approved yet, but soon they made headlines President TrumpDonald John Trump’s Biden campaign attacked Facebook after thousands of ads were blocked by the platform’s pre-election blackout.Mnuchin said he understood the letter Pelosi had sent him, saying that stimulus news “Harris” went to Texas on Friday, after polls showed that Trump and Biden (Biden) There is a connection He said that he received the Regeneron antibody mixture and touted it as a “miracle” and a “cure”.
Although treatment is improving, there is no cure, and the available treatment depends on the patient’s condition.
Director of NIAID Anthony FauciAnthony Fauci is not perfect to hear experts, but it is much worse to ignore them. Fauci: Maybe Fauci expressed support for the national mask authorization before the United States saw “some normal phenomena” in 2022. Said this week that treatment is just a matter of time. Dexamethasone and other steroids can help ventilate critically ill patients, as can the antiviral drug Rexivir. On the other hand, research on experimental antibody therapies shows that they are most effective if taken in outpatients with mild symptoms.