… Immune Mechanisms for an HIV / AIDS Vaccine
By Gabriel Olawale
As efforts to develop a universal preventive human immunodeficiency virus, HIV, the vaccine begins to show promise, the hope of humans, Living with HIV, HIV / AIDS It was rekindled as they waited anxiously, expecting that one day their reproach would turn to joy and all the trauma, stigma and agony would be in the past.
Mrs. Joy Obi, a PLWH-accessible treatment at a Lagos treatment center, said Vanguard that the day a successful universal HIV vaccine is discovered would be her happiest on Earth.
"I'm going to be overjoyed because I would not have to take my meds and the problem of transmitting HIV to babies would not be there."
"I would be like a new creature, a new baby without worries. The stigma would disappear and I would be free from trauma.
According to Joy, many of her friends currently perceive her as a prostitute because she lives with HIV, even though she contracted the virus by splitting a sharp manicure blade.
"I've lost contact with many of my friends because of my status, but I'm getting as good as new with the vaccine," she enthused.
In his view, Mr. Ireti Tobiloba, who said that he came into contact with HIV, his wife found that the existence of a universal preventive HIV vaccine would likely have prevented his infection.
"Usually, when there is an HIV vaccine, I think everyone wants it because people want to live a life without disease." 19659002] "There are many logistical constraints and cost challenges associated with access to lifelong care when living with HIV." In the private market, buying antiretroviral (ARV) medicines at a higher price makes some of the products that are considered to be fake or expired, with the vaccine of the past.
"I know many people who have lost their jobs, Some suffer from social and family isolation, even if the government takes measures to alleviate suffering. Some people lost their job because of their status and the need to miss work because medical appointments or check-ups will not be back.
"So, continue research to find a cure that controls the virus without antiretroviral treatment (ART) remains an important step towards ending the epidemic."
As Nigeria this year, the world community commemorates HIV – Inaugurated on May 18, experts expressed their concern that Nigeria may not benefit from a preventive HIV vaccine if it does not now intervene in its development.
An HIV vaccine is a vaccine that either protects individuals who do not have HIV to become infected with the virus, or otherwise have a therapeutic effect on individuals with HIV contracting later HIV
In the views of Senior Research Scientist with the Nigerian Institute of Medical Research, NIMR, Onwuamah Chika, the HIV strain varies worldwide and even one Nigerian has one
He revealed that in Nigeria, the predominant type of HIV strain in the southern part of the country is different as in the northern part of the country, "HIV 1 subtype G is found in the southern part of the country. In contrast, CRFO2_AG is more of a land in the northern part of the country."
"As a country, we need to get involved in HIV vaccine research because our HIV strain differs from other parts of the world. In other words, if they continue to do research with another strain, it might not work for us once the vaccine is available.
Chika, expressing her dissatisfaction with the current state of the Nigerian Vaccine Laboratory in Yaba, Lagos, called on the government to reactivate the laboratory.
"Nigeria has a high load of people who can really be used for HIV experiment Nigeria can help to generate information about the species we have and to ensure that the type of healing that they bring He pointed out that there are limits in NIMR.
"For example, this lab I work in is Level 2, for example, we will not be able to do much research on Lassa Fever because we need a much higher level of security and such things need money to get and get it.
"We have many colleges in Nigeria, but not many of them have a quality rating and look out for these things before they come. People keep asking why some studies are done in Uganda or Kenya and not in Nigeria. What I tell people is that these countries do not have that much, but what they have is standard.
"What we need to do is strengthen our system, you can not have such technology and say that you are active strike and you can not come to work, many of the laboratories that have been funded and maintained by some of these donor organizations , are now being handed over to the government, but there is a lot of money to manage Many of the laboratories in the country have no personal and financial resources to work with it.
Dr Oliver Ezechi, Deputy Research Director of NIMR, confirmed his view that the world has made progress on HIV. "Several decades ago at this NIMR clinic, people are seen coming and dying every morning. They see people trying to get them out of the vehicle and they're already dead.
"But if you look at this clinic now, we do not have people who are so sick again, so what it means Parents with HIV-positive children may now have HIV-negative babies. "
He explained that investing in research goes beyond financial commitments:" These include building capacity, infrastructure and others – if you give me $ 20 million and I have no people I could work with, equipment and environment, then the money will just be a waste, so it's a systematic planning.
"The first thing the country has to do is make sure that we have master's and doctoral students interested in research. Vaccine research is not something you only wake up for one day and says you want to start.
"Financial investment in government research must be consistent and have nothing to do with a change in administration – if you lose $ 50 million today and nothing next year, you will not succeed."
"Individual and co-operative Organizations have been investing in the HIV cure for more than three decades, so the research is capital intensive and the government has to detect it. Research and innovation are estimated at a certain annual amount.
The program manager of the New HIV Vaccine and Microbicide Advocacy Society, Durueke Florita, said they are committed to a supportive environment to support HIV research in Nigeria
to promote the creation of national policies and programs that are ethical Promote research behavior in Nigeria. We look forward to working with other global partners in the field to see that the world can have an HIV vaccine and that Nigeria will not be left behind in the HIV vaccine business.
"We support communities and build their capacity to understand the problem of HIV vaccine and how they can support it.We are looking for effective vaccines that the community can use that are cost-effective, available, accessible, and most importantly, vaccine delivered as a comprehensive prevention package for the community.