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Home / US / Head of Warp Speed: The United States has to wait until April to get AstraZeneca vaccine

Head of Warp Speed: The United States has to wait until April to get AstraZeneca vaccine



Questions about vaccines: The United States has ordered 300 million doses of the candidate vaccine for two injections, which is facing doubts in the development process. A late-stage trial was suspended this fall to assess severe reactions to injections, and the promising results of early reading of injections were attributed to dose errors.

Sloy said that although the AstraZeneca vaccine appears to be very effective against serious diseases, its efficacy in the elderly is “actually unknown” because few elderly people participate in the trial. He said that given the impact of the virus on the elderly, this is still his biggest problem with shooting against the company.

British regulators became the first person in the world to approve the use of AstraZeneca vaccine on Wednesday morning. British health officials said that they will not delay the dose to ensure that people get the second shot quickly, but will give the country a wide range of first doses and provide a second dose within three months. They said the move will provide a certain degree of protection for the entire country from climbing infections and a new variant of the virus that seems to be more easily spread.

However, the effectiveness of the AstraZeneca vaccine is unclear, especially when the doses are spaced apart. So far, AstraZeneca’s vaccine has been used separately in two full doses, with an interval of 28 days, showing 62% efficacy. However, after a dilution error occurred in a group of a phase 3 trial, scientists found that when a group received a half dose first, the vaccine was 90% effective.

U.S. regulators need more evidence: The drug maker said that the combined results showed a 70% efficacy, but Slaoui suggested that US regulators are not satisfied with the conclusion.

“As far as Americans are concerned, it is important to say that the efficacy of one vaccine is 95% and the efficacy of the other vaccine is X%, regardless of the number,”

; Slaoui told reporters, referring to the high efficiency of Pfizer and BioNTech . Moderna vaccine authorized by the FDA. “We need a clear and specific number, not a number accumulated by adding together different experiments with different timetables and different materials.”

Sloughe also questioned the British dosing strategy. He said it might be more effective to administer the drug in a few months, but he said the UK’s decision was based on theory rather than evidence.

He said: “I think it is important to use vaccines according to your research methods.”


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