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Global COVID-19 prevention trial to restore hydroxychloroquine



LONDON (Reuters)-A global trial to test whether the anti-malarial drugs hydroxychloroquine and chloroquine can prevent COVID-19 infection will be restarted after approval by UK regulators.

FILE PHOTO: On June 16, 2020, a pharmacist showed a box of hydroxychloroquine at the de la Citadelle hospital in the CHR Center Hospitalier area during the Coronavirus Disease (COVID-19) in Liege, Belgium. REUTERS / Yves Herman

After another UK trial found that hydroxychloroquine had no therapeutic benefit for patients already infected with COVID-19, the US Drug Administration (MHRA) made a decision on the so-called COPCOV trial. New coronavirus.

After the results of the treatment trial were released, the COPCOV study was suspended pending review.

This is a randomized, placebo-controlled trial aimed at recruiting 40,000 healthcare professionals and other high-risk individuals worldwide, and is led by the Mahidol Oxford Tropical Medicine Research Group (MORU) at Oxford University in Bangkok, Thailand.

US President Donald Trump said in March that hydroxychloroquine may change the rules of the game, and then said that even after the US regulatory agency Food and Drug Administration (FDA) informed that its efficacy and safety had not been verified, He still takes it himself.

After trials showed that they were ineffective as a treatment, the FDA subsequently revoked the emergency use authorization of the drug for the treatment of COVID-19.

But Nicholas White, an Oxford professor who co-chaired the COPCOV trial, said that research on this drug as a potential preventive drug has not yet given a conclusive answer.

He said in a statement: “Hydroxychloroquine can still prevent infection, which needs to be determined in a randomized controlled trial.” “The question of whether (it) can prevent COVID-19 remains the same as before.”

White’s team said it will resume recruitment of British health workers this week, and said it is planning to open new medical points in Thailand and Southeast Asia, Africa and South America. The result is expected to be achieved by the end of this year.

According to Reuters statistics, COVID-19 caused more than 500,000 deaths on Sunday, and the number of reported cases worldwide has exceeded 10 million.

Reporting by Kate Kelland, editing by Paul Sandle and Timothy Heritage

Our standards:Thomson Reuters Trust Principles.

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