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Fish oil and vitamin D supplements are not effective in preventing atrial fibrillation



Atrial fibrillation

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2-lead ECG shows atrial fibrillation at approximately 150 beats per minute. Image credit: James Heilman, MD/Wikipedia/CC BY-SA 3.0

According to the latest research published today at the American Heart Association’s 2020 Scientific Conference, taking omega-3 fatty acids and vitamin D3 supplements neither increases nor reduces the risk of atrial fibrillation.

Atrial fibrillation is a fast, irregular heartbeat caused by chaotic electrical signals in the top chamber of the heart. Atrial fibrillation is the most common arrhythmia. It can cause blood clots, stroke, heart failure and other heart-related complications. The risk of atrial fibrillation increases with age, high blood pressure, and heavy drinking, and is common in multiple biologically related family members.

The evidence from previous observational studies is conflicting, suggesting the risks and potential health benefits of fish oil (a source of omega-3 fatty acids) and vitamin D for atrial fibrillation.

Christine M. Albert, MD, founding director of the Department of Cardiology at the Cedars-Sinai Smit Heart Institute, said: “Once established, atrial fibrillation is difficult to treat and can cause symptoms that impair the patient’s quality of life.” Los Angeles Medical Center, this study The main author. “Current treatment options limit long-term success and there are significant risks, so prevention strategies are urgently needed.”

VITAL Rhythm Trial is the first placebo-controlled randomized clinical trial to study the preventive treatment of atrial fibrillation. The trial evaluated whether supplementation of vitamin D3 (2000 IU/day) and omega-3 fatty acids (EPA:DHA ratio of 1.2:1; 840mg/day) compared with placebo can reduce the risk of atrial fibrillation.

The 5-year study (from 2012 to 2017) included 25,119 adults aged 50 years and older, none of whom had a history of atrial fibrillation. About half of the participants were women, 21% were black, and the average age was 67. The diagnosis of atrial fibrillation can be determined through participant self-reports and claims data from Medicare and Medicaid Services centers. Confirmation by electrocardiographic evidence and/or a doctor’s report recording a new diagnosis of atrial fibrillation.

During the trial follow-up period, 900 participants developed atrial fibrillation, accounting for 3.6% of the study population. There were no statistically significant differences between the groups assigned to supplementation with EPA/DHA and/or vitamin D3 compared to the individuals assigned to placebo.

Albert added: “In terms of clinical care, these results do not support the use of marine omega-3 fatty acids or vitamin D to prevent AF. However, these results do ensure that these supplements do not increase the overall risk of AF, and It seems generally safe for patients taking these supplements for other reasons.”


Atrial fibrillation is not as lethal as before, but it still deserves attention


More information:
Speech: Conference: LBS.01. Heart failure and atrial fibrillation: vitamins, minerals, nutrients, etc., www.abstractsonline.com/pp8/? _…3#! / 9144 / session / 828

Provided by the American Heart Association

Citation: Fish oil and vitamin D supplements are not effective in preventing atrial fibrillation (November 13, 2020), from https://medicalxpress.com/news/2020-11-fish-oil-vitamin-d on November 14, 2020 -supplements.html search

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