When reports of severe allergic reactions among people reporting the Covid-19 vaccine began, Angelina Giunta was worried.
Although Giunta, 61, of Brooklyn, New York, was eager to get a vaccine after a year of isolation and quarantine, she had two severe allergic reactions to the drug during her cancer treatment in 2017.
Giunta said: “I want to get the vaccine because I want to keep going.” “But I’m very worried.”
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The two components in the Covid-19 vaccine, polyethylene glycol and polysorbate 80, are believed to be the culprits of allergic reactions related to the Covid-1
Nevertheless, some allergy clinics across the United States have begun to emphasize that they can test patients’ allergies to these ingredients.
However, many experts say that these tests can waste time and resources-mainly because this type of allergy is very rare.
A colleague of mine who has been allergic for 20 to 30 years, on the one hand, can calculate the number of patients they see with polyethylene glycol reactions.
Dr. Paul Williams, an allergist at the Seattle Northwest Asthma and Allergy Center, said: “My colleagues who have been working with allergy for 20 to 30 years can count the number of patients they have seen with polyethylene glycol reactions on one hand.” Clinical Professor of Pediatrics, University of Washington.
In fact, the vast majority of Americans are likely to have been exposed to polyethylene glycol or polysorbate 80.
Polyethylene glycol is a common active ingredient in over-the-counter laxatives. Pfizer BioNTech and Moderna use it as a protective layer of messenger RNA or mRNA in their vaccines, which is part of the genetic code used to teach cells how to recognize and fight the virus that causes Covid-19.
In the typical American diet, polysorbate 80 is ubiquitous in chewing gum, ice cream, pudding and other foods. Used as an emulsifier to make the product creamier. It is also a component of the Johnson & Johnson Covid-19 vaccine that has been identified as a potential allergen, although to date, J&J vaccine recipients have not reported allergic reactions.
Dr. Mitchell Grayson, chair of the Asthma and Allergy Foundation of the American Council of Medical Sciences, said: “In terms of allergic diseases or allergic reactions, these vaccines are nothing special.” “Why don’t we usually see more Of people suffer from polyethylene glycol or polysorbate allergies?”
The Centers for Disease Control and Prevention said in a statement to NBC News that the incidence of severe allergic reactions to the Covid-19 vaccine is “2 to 5 people per million people in the United States.” “Fortunately, vaccinators have medicines that can be used to effectively and immediately treat patients who experience allergic reactions after vaccination.”
In addition, the Covid-19 vaccination program has taken the factors of screening and monitoring such reactions into consideration: this is why the vaccinators should be asked in advance if they have had a severe allergic reaction to the vaccine before, and why they should be told to wait 15 to The reason why it takes 15 minutes to get the vaccine. 30 minutes after vaccination, so if a reaction does occur, the medical staff can respond.
Grayson said that the biggest problem with the Covid-19 vaccine is not allergies, but hesitation. Nearly one-third of those who participated in a recent survey by the Kaiser Family Foundation said they would rather wait and see what happens to other vaccinated people before they roll up their sleeves.
Speaking of the Covid-19 vaccine allergy test, Grayson said: “My concern is that all of this will only contribute to this situation.”
Who (if anyone) needs testing?
The Charleston Allergy and Asthma Hospital in South Carolina is a clinic that provides testing for polyethylene glycol and polysorbate 80. The test is performed by putting a small amount of the problematic substance into the skin of a person and observing whether there is a reaction (such as redness or itching).
“We don’t yet know what it is [vaccine] Dr. Meredith Moore, a physician at the clinic, said: “These ingredients cause reactions in all these different individuals. But when you look at the ingredients of these two vaccines, polyethylene glycol and polysorbate are more likely to be the culprits. The culprit.”
So far, none of the tests performed in Moore’s patients have been positive.
Moore said that most people with allergies do not need to worry about any potential reactions to the Covid-19 vaccine.
In fact, for people who carry emergency adrenaline to treat peanuts, insects or other allergies, Moore advises against being tested. She said allergy tests for polyethylene glycol or polysorbate 80 should be reserved for people who have a history of allergic reactions without any known cause.
Merck’s former executive director of vaccine medical affairs, former Department of Defense immunologist John Grabenstein (John Grabenstein) said that there is no evidence that these tests can reduce the risk of any type of allergic reaction caused by the Covid-19 vaccine.
Since these ingredients have not been proven to be the cause of allergic reactions to the Covid-19 vaccine, a negative allergic reaction to polyethylene glycol or polysorbate 80 does not necessarily mean that allergic reactions to the vaccine can be exempted. Experts say that a positive test should not exclude people from getting the Covid-19 vaccine.
Grabenstein said: “The vast majority of the public-even people with pollen allergies, people allergic to penicillin and bees-don’t have to worry about getting vaccinated.”
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Dr. Cascya Charlot agreed with the tests provided during his internship at the Brooklyn Allergy and Asthma Care Center.
Charlotte said: “I’m not advocating for everyone to have a skin test before being vaccinated, absolutely not.”
She sees testing as a way to alleviate the fear of allergic reactions to the Covid-19 vaccine.
Charlotte said: “As far as we can see, this is a public health incentive to try to get people vaccinated.” “We don’t want to worry about the potential response of this vaccine.”
Charlotte’s allergy test to polyethylene glycol or polysorbate 80 did not return to positive.
Grayson said the danger of relying on such tests is that someone “avoids vaccines that they should have been able to accept.”
Grayson said: “You either unnecessarily exclude people from the vaccine, or let them continue to vaccinate, not sure whether it will cause allergic reactions.”
A positive effect seems to be peace of mind.
Giunta, a patient in Charlotte, tested negative and she is looking forward to her Covid-19 vaccine.
Giunta said: “I want to continue my life and travel and do the normal things I have done before.”
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