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Home / Business / After destroying 15 million Covid-19 vaccine doses, Johnson & Johnson will take over the factory

After destroying 15 million Covid-19 vaccine doses, Johnson & Johnson will take over the factory



After an error at a manufacturing plant in Baltimore last week, millions of doses of Johnson & Johnson’s Covid-19 vaccine were destroyed. The Biden government announced on Saturday that Johnson & Johnson will be responsible for the plant.

The plant is affiliated to the manufacturing contractor Emergent BioSolutions and has previously produced two Covid-19 vaccines, of which only Johnson & Johnson’s bullets have been approved for emergency use in the United States. According to the “New York Times” report on Saturday, with the company’s control, Johnson & Johnson will become the only vaccine produced at the plant.

The Johnson & Johnson injection approved by the U.S. Food and Drug Administration (FDA) in late February is a single shot vaccine. Unlike the mRNA-based Covid-1

9 vaccines produced by Pfizer/BioNTech and Moderna, the vaccine requires two doses to be fully effective. And it only needs a refrigerator, not a freezer for storage.

It is also very effective-clinical trial results show that despite the worry about the accumulation of Johnson & Johnson’s pills after 4 weeks, it can prevent about 85% of “severe and severe Covid-19 cases” and 100% of deaths and hospitalizations. Shots of Pfizer and Moderna.

As Vox’s Umair Irfan explained last month,

[Johnson & Johnson] The report states that its overall efficacy in preventing symptomatic Covid-19 cases is 66.1%. The efficacy level of Moderna vaccine and Pfizer/BioNTech vaccine is about 95%.

The gap in efficacy numbers has exacerbated some people’s perception that Johnson & Johnson’s Covid-19 vaccine is not effective.

However, according to Dr. Amesh Adalja of Johns Hopkins University, this direct comparison is fraught with challenges, and these vaccines are “basically interchangeable.”

“I didn’t even look at these efficacy numbers, but compared them head-on like this,” Adalja told Vox. “Biostats 101: You cannot compare test results like this unless they are done head-to-head.”

Johnson & Johnson said in a statement that it is “taking full responsibility for manufacturing at the Baltimore plant” and will “significantly” increase its staff there.

According to The Times, the error that led to Johnson & Johnson’s announcement on Saturday-destroying approximately 15 million vaccine doses-was produced after mixing different vaccine vectors used by Johnson & Johnson and AstraZeneca. The two vaccines are incompatible. .

However, Johnson & Johnson emphasized in a statement on Wednesday that it will continue to seek emergency use authorization for the emergency Baltimore facility and will still meet its vaccine delivery goals.

Johnson & Johnson plans to provide another 24 million doses of vaccine by the end of April, and nearly 100 million doses of vaccine by the end of May. President Joe Biden promised that every American adult will be eligible for the Covid-19 vaccine by May 1, and recently set a new goal that by the end of his first 100 days in office, 200 million shots will be fired.

In a statement on Saturday, AstraZeneca, which developed another vaccine produced at the emergency plant in Baltimore, said it was working to “identify an alternative location for production.”

According to the “New York Times” report, last year, the United States invested in AstraZeneca (AstraZeneca) dose reserves for use in the United States, but has not yet obtained emergency use authorization.

However, even before Saturday, AstraZeneca’s Covid-19 vaccine was in trouble because the company hopes that it will become the fourth coronavirus vaccine authorized for emergency use in the United States.

According to Umair Irfan of Vox, in March, the National Institutes of Health’s independent advisory committee criticized the company for using “outdated and potentially misleading” efficacy data in its press release. Since then, AstraZeneca has released more complete data, showing a slightly lower (but still strong) effective rate of about 76%.

In addition, after regulatory agencies in several European countries suspended the distribution of the AstraZeneca vaccine due to thrombosis concerns, it attracted widespread attention last month, but the European Union has since concluded that the injection is “safe and effective.”

Despite the findings of EU regulators, AstraZeneca vaccine has not yet been approved for use in the United States. Therefore, the Biden administration announced in March that it would send a certain dose of the vaccine from US stocks to AstraZeneca to Canada and Mexico, both of which have approved the use of the vaccine.

Mass vaccination efforts in the U.S. are accelerating

Although Johnson & Johnson and AstraZeneca suffered setbacks last month, the current US vaccine news is definitely good news. With the increase in the three coronavirus vaccines approved for emergency use and distribution, the country continues to create vaccination records.

According to White House Covid-19 adviser Andy Slavitt (Andy Slavitt), on Saturday, the United States received more than 4 million vaccines, making the week’s average level of more than 3 million doses per day for the first time.

In addition, CNN’s Ryan Struyk tweeted on Friday that more than 100 million people in the United States now receive at least one dose of the Covid-19 vaccine. According to Struyk, as of Saturday, this means that two-fifths of American adults have received at least one dose.

There is also positive news about the effectiveness of several Covid-19 vaccines that have been approved for use in the United States.

A new study last week confirmed that even after a single injection, Pfizer/BioNTech and Moderna vaccines can provide substantial protection against Covid-19 under realistic conditions.

According to research, both vaccines are about 80% effective after the first dose and 90% after both doses.

The Wall Street Journal also reported on Thursday that the Pfizer vaccine “remains highly effective six months after the second dose, indicating that this protection may last longer.”

Nevertheless, despite the good news, Dr. Rochelle Varensky, director of the Centers for Disease Control and Prevention, urged caution.

She said last week: “We have too many expectations, the prospects and potentials we are in and the reasons for hope, but now I am scared,” she warned that Covid-19 cases in the United States have begun to happen. Climb again.

According to coronavirus data tracked by the New York Times, cases in the United States have increased by 19% in the past two weeks. As of Saturday, an average of nearly 65,200 boxes per day for seven consecutive days.

Valensky said: “We are almost there, but we are not there yet.” “So I would like to ask you to wait a moment to get vaccinated if possible, so that when this pandemic is over, we Everyone who everyone loves is still here.”




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