Gut microbiologists have an idea about how diet affects the gut microbiome, but there is no large amount of data to provide evidence that there is a relationship between the two.In the paper published on Monday Natural medicineThe collaboration of gut microbiome researchers from multiple institutions provided the first evidence linking diet to the gut microbiome.
The authors of the study included researchers from King’s College London, Harvard University’s Chenhe School of Public Health, Massachusetts General Hospital (MGH), University of Trento, Italy, and researchers from the health science startup ZOE Global.The study called PREDICT 1
Participants in the PREDICT 1 study sequenced their gut microbiota by the study authors. They also provided detailed long-term dietary information and blood samples. Researchers have found that there is a significant correlation between microorganisms, nutrients and food types. The author believes that food quality (unprocessed and highly processed), food source (plants and animals), and food type (healthy and unhealthy) are essential for overall health and microbiome ecology.
In particular, the research results show that the diversity of healthy plant-based foods in the diet “shapes the composition of the gut microbiome.” Another interesting finding is that researchers can identify microbial indicators of obesity in everyone. Researchers are able to identify metabolites in the blood, which can be used as biomarkers to indicate the risk of cardiovascular disease.
@cibiocm @nsegata @fasnicar’s new paper is now published in @NatureMedicine
# Microorganisms and the host’s connection# Metabolism and habitual diet# From 1,098 individuals with deep phenotype
➡️https://t.co/31q9sMzBQq#CIBIOpaper #metagenomics pic.twitter.com/t9Wz211vlc
— CIBIO-UniTrento (@CIBIO_UniTrento) January 12, 2021
According to the press release, Nicola, a professor and principal researcher at the Computational Metagenomics Laboratory of the University of Trento, said Italy is the head of the microbiome analysis in the study.
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The results of this study indicate that we may be able to influence which microorganisms can survive in the gut based on our diet. Tim Spector, an epidemiologist at King’s College London, is the scientific founder of ZOE. The company funded and supported this research and launched the PREDICT research program. He said: Not only is it nourishing the body, it is feeding trillions of microorganisms living in the intestines.”
The company plans to promote this science and technology to the public.
“Through ZOE, we can now provide an opportunity to discover which microorganisms live in their gut,” Spector said in a press release. “By using machine learning, we are able to share with you our calculations of your body’s response to any food.”
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The next step of the research is to start clinical trials to test whether people can change the gut microbiome by changing their diet, hoping to increase the level of good microorganisms relative to bad microorganisms. New York Times.
Sarah Berry, a nutritionist at King’s College London and co-author of the study, said: “We think that people can make many small changes that may have a major impact on microbial health.” The New York Times.
The next phase of the research, PREDICT 2, is a collaboration between ZOE, Massachusetts General Hospital and Stanford University, and data collection will be completed in 2020. Fiana Tulip, head of communication at ZOE, said that the main goal of this study is to better understand dietary intake, including meal times and time of day. According to the press release, PREDICT 3 was launched a few months ago. Tulip said in an email to “Change America” that its goal is to verify and “understand the impact of ZOE dietary recommendations on weight, health and well-being.”
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