Deadline learned that just as California seems to be about to truly turn the edge of Covid-19, the Stanford University Clinical Virology Laboratory confirmed a case of an emerging variant originating in India.
Lisa Kim, Stanford University Healthcare Media Relations Senior Manager, said: “Stanford University Healthcare’s clinical virology laboratory identified and confirmed the newly described “India” variant last week. This variant has what was found in the CA variant. L452R mutation, and another important spike mutation E484Q. In South Africa and Brazil (P.1 and P.2) variants, this same position is mutated to a different amino acid (K).”
In more conversational terms, this means that a variant of the Indian variant is like the key variant first discovered in the so-called Brazilian and South African variants. Another mutation was also found in a mutation first discovered in California, which is the most widespread new strain in the state so far.
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The news was first reported by the “San Francisco Chronicle”.
This development is interesting because it brings together worrying mutations from interesting independent variants for the first time.
Peter Chin-Hong, an infectious disease expert at the University of California, San Francisco (UCSF), told the Chronicle on Monday: “This Indian variant contains two mutations in the same virus for the first time. It used to be in separate variants. “As we know that the affected domain is the part that the virus uses to enter the human body, and the California variant is already more resistant to certain vaccine antibodies, it seems reasonable to think that the Indian variant might That too.”
Stanford University’s King warned: “It’s not clear whether this variant is more infectious or resistant to vaccine antibodies.” In fact, despite the surge in cases in India in recent weeks, the Associated Press reported that at the end of March, Officials are more worried about the spread of British variants rather than double variants.
However, news of the new abnormal strain has raised concerns about the California variant, especially because one of the mutations was also found in one of the most widespread strains in the state.
As of April 1, California has been tracking five interesting variants, including the United Kingdom (B.1.1.7), Brazil (P.1 and P.2), South Africa (B.1.351), and of course There are its natively grown West Coast variants (B.1.427 and B.1.429). See below.
Jin said there was a “confirmed case of double mutation” [genomic] Sequencing was performed at Stanford University, and it was estimated to be 7 through screening RT-PCR. “These numbers may seem small, but consider the following: In California, only a very small number of test samples are labeled for genomic analysis.
For example, California has managed more than 55 million Covid-19 tests. Of these, less than 50,000 are marked by doctors for genome sequencing. This means that less than 0.01% of the samples have been tested. It is true that the samples that have been tested have been marked by experts, but in a region of 40 million, which is also the most used state among unions, such monitoring cannot provide reliable insights to understand the spread of these variants.